ISSN 1662-4009 (online)

ey0016.6-14 | Food for Thought in Transgender Medicine | ESPEYB16

6.14 Genetic link between gender dysphoria and sex hormone signaling

M Foreman , L Hare , K York , K Balakrishnan , FJ Sanchez , F Harte , J Erasmus , E Vilain , VR Harley

J Clin Endocrinol Metab. 2019 Feb 1;104(2):390–396.doi: 10.1210/jc.2018-01105. PubMed PMID: 30247609.Polymorphisms in sex hormone genes have been described in gender dysphoric individuals with inconsistent findings. In this case-control study of 380 trans women and 344 control males, functional variants in 12 sex hormone signaling genes were studied. Significant a...